产品货号：
Z11492
中文名称：
BBS5抗体
英文名称：
Anti-BBS5 antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-BBS5 antibody |
| 指标别名 | Bardet Biedl syndrome 5;BBS5 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,IP,ELISA |
| 基因名称 | BBS5 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human BBS5 recombinant protein (Position:M1-E338). |
| 实际分子量 | 39KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia.The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor,which localizes to the basal body and contacts the BBSome.Rab8 (GTP) enters the primary cilium and promotes extension of the ciliary membrane.Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8,the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane.The BBSome complex,together with the LTZL1,controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation.Required for BBSome complex ciliary localization but not for the proper complex assembly. |
| Uniprot ID | Q8N3I7 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 基因名全称 | Bardet-Biedl syndrome 5 |
| 蛋白名全称 | Bardet-Biedl syndrome 5 protein |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 ImmunoPrecipitation (IP) 1:50 Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
相关搜索：BBS5抗体，BBS5多抗，Anti-BBS5 antibody